Vaccinations for Peru
Peru is a complex and rewarding destination for Canadian travellers — Lima, Cusco, Machu Picchu, the Sacred Valley, and Amazon jungle tours all have distinct health considerations. Altitude sickness is a major concern for Cusco and Machu Picchu visitors; malaria and Yellow Fever are required for Amazon travel.
Recommended vaccines for Peru
Required for entry
- Yellow Fever (required for Amazon jungle travel — Iquitos, Madre de Dios, Puerto Maldonado)
- Hepatitis A (all travellers)
- Typhoid (all travellers)
- Dukoral (recommended for GI protection)
- Yellow Fever (Amazon regions — essential)
- Malaria prophylaxis (Amazon regions — Iquitos, Puerto Maldonado, jungle lodges)
- Rabies pre-exposure (Amazon and rural travel)
Malaria risk & prevention
Malaria is present in the Peruvian Amazon — Iquitos, Puerto Maldonado, Madre de Dios, and Amazon jungle tours require prophylaxis. Lima, Cusco, Machu Picchu, and the Sacred Valley are malaria-free (high altitude). Our physician reviews your itinerary.
Key health considerations
- 1Altitude sickness is the primary health risk for Cusco and Machu Picchu visitors — acclimatization protocol and acetazolamide (Diamox) prescription available from our physician.
- 2Yellow Fever is endemic in the Peruvian Amazon — vaccination is required for jungle travel.
- 3Traveller’s diarrhea is a significant risk across Peru — Dukoral + standby antibiotic recommended.
Travel-health tips
- Arrive in Cusco 1–2 days before Machu Picchu and acclimatize — altitude sickness can ruin the highlight of the trip.
- Carry physician-prescribed acetazolamide (Diamox) for altitude prevention — discuss at your consultation.
- Amazon Peru requires Yellow Fever vaccination and malaria prophylaxis — different preparation than Cusco/Machu Picchu.
Vaccines commonly needed for Peru
Ready to prepare for Peru?
Book a virtual consultation with a licensed Canadian physician. We will build your personalized vaccine plan and administer everything at our Toronto pharmacy.
Book your consultationFrequently asked: Peru
Do I need malaria pills for Machu Picchu and Cusco?
No — Machu Picchu and Cusco are at high altitude (3,400 m and 3,300 m) and are completely malaria-free. No malaria prophylaxis required for standard Inca Trail and Sacred Valley itineraries. Malaria prophylaxis IS required if you extend your trip to Amazon Peru (Iquitos or Puerto Maldonado).
What is altitude sickness and how do I prevent it in Cusco?
Altitude sickness (Acute Mountain Sickness / AMS) affects approximately 25% of travellers arriving in Cusco (3,400 m). Symptoms: headache, nausea, fatigue, dizziness — usually within 6–12 hours of arrival. Prevention: arrive 1–2 days early, rest, avoid alcohol, stay hydrated. Our physician can prescribe acetazolamide (Diamox) which significantly reduces AMS risk when started 1–2 days before ascending.
Do I need Yellow Fever vaccine for Peru?
Yellow Fever vaccination is required if you are visiting the Peruvian Amazon (Iquitos, Puerto Maldonado, Amazon jungle lodges, Manu National Park). For Lima, Cusco, Machu Picchu, and the Sacred Valley — no Yellow Fever required. If your Peru itinerary includes both Cusco AND an Amazon extension, get vaccinated.
Related reading for Peru travellers
Explore other destinations
This information is for educational purposes and reflects common recommendations for healthy adult Canadian travellers. Individual recommendations depend on your health history, itinerary, and current advisories from the Public Health Agency of Canada and WHO. A consultation with our physician is required before any prescription is issued.