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Malaria Prevention

Malaria is a potentially fatal parasitic illness transmitted by Anopheles mosquitoes. There is no vaccine approved for travellers; prevention relies on prescription antimalarial medication combined with strict mosquito-bite prevention.

Protects against
Plasmodium falciparum
Doses
Daily or weekly pill starting before travel, continuing during, and for 1–4 weeks after, depending on drug
Schedule
Malarone: 1–2 days before | Doxycycline: 1–2 days before | Mefloquine: 2 weeks before
Duration
Only while taking the medication — there is no long-term immunity. Must be combined with mosquito-bite prevention.

What it protects against

Plasmodium falciparum, P. vivax, P. ovale, P. malariae, P. knowlesi — parasites that cause malaria.

Who should get it

  • Travellers to malaria-endemic areas (sub-Saharan Africa, parts of Asia, South/Central America)
  • Pregnant travellers (with careful drug selection)
  • Visitors to rural/jungle regions of malaria-risk countries

Not recommended for

  • Each drug has specific contraindications — our physician reviews carefully
  • Doxycycline: children under 8, pregnancy
  • Mefloquine: history of depression, anxiety, seizures

Destinations where Malaria is recommended

Most of sub-Saharan Africa (Kenya, Tanzania, Ghana, Uganda, Nigeria)
India (most areas below 2,000 m)
Papua New Guinea, Solomon Islands
Amazon regions of Peru, Brazil, Colombia
Select border regions of Thailand, Vietnam, Cambodia

Side effects & safety

  • Malarone (atovaquone-proguanil): well-tolerated; occasional nausea or vivid dreams
  • Doxycycline: sun sensitivity, upset stomach, not for pregnancy
  • Mefloquine: rarely neuropsychiatric effects — not used in people with depression or anxiety

Key facts

  • 1There is no "malaria vaccine" for travellers — prevention is pill-based
  • 2Mosquito-bite prevention (DEET, long sleeves, bed nets) is equally important
  • 3Drug choice depends on destination, duration, health, and cost

Need the malaria prevention for your trip?

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Frequently asked: Malaria Prevention

Which malaria medication is best?

For most Canadian travellers, atovaquone-proguanil (Malarone) is the first-line choice — well-tolerated, daily dosing, only 7 days post-trip required. Doxycycline is a cheaper alternative. Mefloquine is reserved for longer trips and is avoided in travellers with a mental-health history.

Do I need malaria medication for all of Africa?

Almost all of sub-Saharan Africa requires malaria prophylaxis. North African countries (Morocco, Tunisia, Egypt) are largely malaria-free.

Can I just use mosquito repellent instead?

No — mosquito-bite prevention alone is not sufficient in high-transmission areas. Medication plus prevention is the standard of care.

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This information is for educational purposes only and does not replace an individual medical consultation. Recommendations vary based on your health history, destination, and planned activities. A consultation with our licensed physician is required before any prescription or vaccine is issued.